田野

的个人主页 http://teacher.nwpu.edu.cn/tianye

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基本信息 The basic information

田野

生命学院

博士研究生毕业

医学博士

讲师(高校)

tianye@nwpu.edu.cn

工作经历 Work Experience

2016/05-至今,西北工业大学,生命学院,讲师

2013/08-2016/04,第四军医大学,第二附属医院,主管药师

2014/08-2015/10,加州大学戴维斯分校,博士后 

教育经历 Education Experience

2008/09-2013/06,浙江大学,药物化学,博士

2010/11-2011/12,美国华盛顿大学,联合培养博士研究生

2004/09-2008/06,浙江大学,药学,学士学位 

教育教学 Education And Teaching

本科生课程:生命科学导论

研究生课程:蛋白质实验技术;航天医学工程

科学研究 Scientific Research

1 主持科研项目

(1) 国家自然科学基金青年项目:“MACF1通过FOXO1/β-catenin通路调节成骨细胞抗氧化参与模拟失重抑制骨形成的机制研究”(No.81801871

(2) 陕西省自然科学基础研究计划一般项目(青年):“MACF1调控MAP1B参与骨形成的机制研究”(No.2018JQ8032

(3) 中国博士后科学基金面上项目:“MACF1调节细胞氧化还原平衡参与模拟失重抑制成骨分化No.2017M613210

(4) 陕西省博士后科研资助项目:重组小RNA的生物合成及其对失重性骨质流失的治疗作用

(5) 横向项目“重组功能性小RNA生物合成技术”,2017.10-2019.10

(6) 中央高校基本科研业务费“重组功能性小RNA在治疗骨质疏松症中的应用”(No.3102018zy053

(7) 西北工业大学引进高层次人才科研启动费资助项目“MACF1调控小鼠成骨细胞分化的分子机制”,2016.1-2017.12

学术成果 Academic Achievements



[1]   Peihong Su#, Ye Tian#, Chaofei Yang, Xiaoli Ma, Xue Wang, Jiawei Pei, Ai-Rong Qian*, Mesenchymal Stem Cell Migration During Bone Formation and Bone Diseases Therapy, Int J of Mol Sci, 2018, 19(8): 2343

[2]   Ye Tian, Jiang Zheng*, Metabolic Activation and Toxicities of bis-Benzylisoquinoline Alkaloids, Advances in Molecular Toxicology, Elsevier B.V., Edited by James C. Fishbein and Jacqueline M. Heilman, Volume 11, Chapter Six

[3]   Ye Tian, Xiaoli Ma, Chaofei Yang, Peihong Su, Chong Yin, Ai-Rong Qian*, The Impact of Oxidative Stress on the Bone System in Response to the Space Special Environment, Int J of Mol Sci, 2017, 18(10): 2132

[4]   Joseph L. Jilek#, Ye Tian#, Ai-Ming Yu*, Effects of MicroRNA-34a on the Pharmacokinetics of Cytochrome P450 Probe Drugs in Mice, Drug Metab Dispos, March 2, 2017, dmd.116.074344; DOI: https://doi.org/10.1124/dmd.116.074344

[5]   Ye Tian, Shuijie Shen, Yan Jiang, Qi Shen, Su Zeng*, Jiang Zheng*, CYP3A5 mediates bioactivation and cytotoxicity of tetrandrine, Arch Toxicol, 2016, 90(7): 1737-1748

[6]   Ye Tian, Yicong Bian, Yan Jiang, Sainan Qian, Aiming Yu, Su Zeng*, Interplay of Breast Cancer Resistance Protein (BCRP) and metabolizing enzymes, Curr Drug Metab, 2015, 16(10): 877-893

[7]   Ye Tian, Sainan Qian, Yan Jiang, Qi Shen, Jiang Zheng, Hui Zhou*, Su Zeng*, The interaction between human breast cancer resistance protein (BCRP) and five bisbenzylisoquinoline alkaloids, Int J Pharmaceut, 2013, 453(2): 371-379

[8]   Ye Tian#, Ying He#, Haihong Hu, Lu Wang, Su Zeng*, Determination of the enantioselectivity of six chiral aryloxy aminopropanol drugs transport across Caco-2 cell monolayers, Acta Pharmaceutica Sinica B, 2012, 2(2): 168–173

[9]   田野,屈伯宣,姚艳,曾苏*,LLC-PK1/BCRP细胞系的建立及其生物学特征,药学学报,2012,47(12):1599-1604 

[10] Chong Yin#, Yan Zhang#, Lifang Hu, Ye Tian, Zhihao Chen, Dijie Li, Fan Zhao, Peihong Su, Xiaoli Ma, Ge Zhang, Zhiping Miao, Liping Wang*, Airong Qian*, Cory J. Xian, Mechanical unloading reduces microtubule actin crosslinking factor 1 expression to inhibit β-catenin signaling and osteoblast proliferation, J Cell Physiol, 2018, 233(7): 5405-5419

[11] Siyu Li, Zhiping Miao, Ye Tian, Haoyu Wang, Shuai Wang, Tianyuan He, Yue Yang, Peng Wang, Mengyao Ma, Tuanmin Yang, Tao Chen, Zhiyong Liu, Junhong Gao, Chu Chen*, Airong Qian*, Limethason reduces airway inflammation in a murine model of ovalbumin?induced chronic asthma without causing side effects, Exp Ther Med, 2018, 15(3): 2269-2276

[12] Ai-Ming Yu*, Ye Tian, Mei-Juan Tu, Pui-Yan Ho, Joseph L. Jilek, MicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective Therapy, Drug Metab Dispos, 2016, 44(3): 308-319