武祥龙

的个人主页 http://teacher.nwpu.edu.cn/wuxianglong

  被浏览次数:1822

基本信息 The basic information

武祥龙

生命学院

博士研究生毕业

博士

副教授

生物医学工程

wuxianglong@nwpu.edu.cn

13572128286

工作经历 Work Experience

2013年1月至2014年4月西北工业大学生命学院讲师;2014年4月至今生命学院副教授。 

教育经历 Education Experience

2005年毕业于西北大学材料化学专业,2010年获有机化学博士学位,2010年7月至2012年12月西北工业大学生命学院博士后。  

教育教学 Education And Teaching

研究方向:

荧光探针设计合成及应用、航天员空间骨丢失机理及其防护药物研究、药物设计合成及生物活性研究 

主讲课程:

本科生专业课《人体解剖生理学》 

本科生专业基础课《有机化学》

研究生专业课《药物代谢与药物分析》 

教学荣誉

2016年首届卓越联盟青年教师讲课比赛三等奖;

2017年西北工业大学最受欢迎教师称号;

2017年优秀班主任称号;

2018年陕西省第三届微课教学比赛三等奖

教改项目:

2016年获批1项校级在线开放课程建设项目《人体解剖生理学》;

2016年获批1项教学与考核模式改革项目;

中国大学mooc主讲人体解剖生理学

网址链接https://www.icourse163.org/u/mooc1484209761168?userId=1023603365

 

科学研究 Scientific Research


国家自然科学基金青年项目(21202130),用于标记糖的荧光探针的设计合成及其示踪寡糖吸收机制研究2013~2015 

陕西省自然科学基金面上项目(2015JM2067),利鲁唑衍生物的合成及其镇痛作用机制研究2015.1-2016.12


 


学术成果 Academic Achievements

  1. [1]Wu X L, Liu L, Li Y J, et al. Synthesis, crystal structure, and antinociceptive effects of some new riluzole derivatives[J]. Medicinal Chemistry Research, 2018, 27: 1374–1383.

  2. [2]Jing X L, Wu X L(co-first author), et al. Reaction-Based Fluorescent Probes for rapid detection of hydrogen sulfide in vivo[J]. Analytical Methods, 2018,10:4079-4084.

  3. [3]Jing X L, Wu X L(co-first author), et al. A reversible fluorescent probe for Zn2+ and ATP in living cells andin vivo[J]. Sensors and Actuators B, 2018, 261(5):127-134.

  4. [4]Zhang F, Liu L, Wang Q C, Lin X B, Lv W J, Mei Q B, WU Xiang-long*. Recent research progress of regulation signaling pathway of HeLa cells in cervical cancer [J]. Chem Bioeng, 2018, 35(2): 1 - 7 (Chinese).

  5. [5]WANG Qing-chuan, LIU Liu, XU Xiao-kang, GAI Dong-wei, MEI Qi-bing, WU Xiang-long*, Research progress on pharmacology of AMPA receptors' allosteric modulator CX516[J], Chemistry & Bioengineering, 2017, 34(6): 1-5 (Chinese).

  6. [6]JIN Xi-lang, WU Xiang-long(Co-first author), LIU L, et al. Dual-functional fluorescein- based chemosensor for chromogenic detection of Fe3+ and fluorgenic detection of HOCl [J]. Journal of Fluorescence, 2017(4): 2111-2117.

  7. [7]LIU Liu, WANG Qing-chuan, GAI Dong-wei, XU Xiao-kang, XU Qiang-qiang, HE Chong, CHEN Wei, WU Xiang-long*, The research progress on neuroprotective, analgesic and anti-depressant of riluzole [J], Chemistry & Bioengineering, 2017, 34(2): 6-9 (Chinese).

  8. [8]WU Xiang-long, LIU Liu, LI You-Jia, LUO Jie , GAI Dong-Wei, MA Jing-Chuan, MEI Qi-Bing, Synthesis and crystal structure of 2-(N-cyclohexylamine)-6-trifluoromethoxy- benzothiazole [J], Chinese Journal of Synthetic Chemistry, 2016, 24(4): 346-349(Chinese).

  9. [9]Qi Hong-fei, Ye Zhi-hong, Ren Hai-long, Chen Na-na, Zeng Qing-yan, Wu Xiang-long, Lu Ting-li, Bioactivity assessment of PLLA/PCL/HAP electrospun nanofibrous scaffolds for bone tissue engineering [J], Life Sciences, 2016, 148: 139-144.

  10. [10]LIU Liu, MA Jing-chuan, GAI Dong-wei, ZHANG Yan, FENG Xin, MA Meng-yao, ZHANG Ming, WU Xiang-long*, Progress in the application of fluorescent probe for detecting thiol compounds [J], Chemistry & Bioengineering, 2016, 33(2): 1-7(Chinese).

  11. [11]SHANG Peng, HUYAN Ting, YANG Zhou-qi, WU Xiang-long, ZHAO Yu-fen, ZHAO Guo-ping, GU Yi-dong, Tendency and critical scientific issues of space life science in China [J], Sci Sin Tech, 2015, 45: 796-808(Chinese).

  12. [12]SHANG Peng, HUYAN Ting, YANG Zhou-qi, WU Xiang-long, GU Yi-dong, Prospect of space life science study on China Space Station [J], Manned Spaceflight, 2015, 21(1): 1-5 (Chinese).

  13. [13]LIU Hao, ZHANG Jun, ZHANG Bin, YE Zhi-hong, ZHANG Kai-guo, WU Xiang-long*, Research progress on bioactives and labeling technique of oligosaccharide [J], Shandong Chemical Industry, 2015, 44(3): 40-45(Chinese).

  14. [14]Wu Xiang-long, Tian Min, Fan Wu-tu, Pan Ya-lei, Zhai Yuan-kun, Niu Yin-bo, Li Chen-rui, Lu Ting-li, Mei Qi-bing, Synthesis, spectroscopic properties, and biological applications of eight novel chlorinated fluorescent proteins-labeling probes [J], Journal of Fluorescence, 2014, 24(3):775-786.

  15. [15]Wu Xiang-long, Fan Wu-tu, Pan Ya-lei, Zhai Yuan-kun, Niu Yin-bo, Li Chen-rui, Mei Qi-bing, Synthesis, crystal structure and anti-fatigue effects of some benzamide derivatives[J], Molecules, 2014, 19(1):1034-1046.

  16. [16]Fan Wu-tu, Wu Xiang-long, Pan Ya-lei, Li Chen-rui, Niu Yin-bo, Zhai Yuan-kun, Mei Qi-bing, 1-(1,3-Benzodioxol-5-yl-carbo-nyl) piperidine, a modulator of alpha-amino-3- hydroxy-5-methyl-4-isoxazole propionic acid receptor, ameliorates exercise-induced fatigue in mice[J], Biological & Pharmaceutical Bulletin, 2014, 37(1):13-17.

  17. [17]FAN Wu-tu, WU Xiang-long, PAN Ya-lei, ZHAI Yuan-kun, MEI Qi-bing, Synthesis of 3, 4, 5-trimethoxybenzamides and antifatigue activities[J], Chinese Journal of Pharmaceuticals, 2014, 45(4): 312-314(Chinese).

  18. [18]WU Xiang-long, LI Hai-liang, LU Na, NIU Yin-bo, LI Chen-rui, MEI Qi-bing, Research on bioactives and structure-activity relationships of the benzothiazole derivatives[J], Chemistry & Bioengineering, 2014, 31(5): 1-6 (Chinese) .

  19. [19]Wu Xiang-long, Fan Wu-tu, Synthesis, spectroscopic properties, and cell imaging of novel chlorinated fluorescent proteins-labeling probe[J], Journal of Life Sciences and Technologies, 2013, 1(4): 210-215.

  20. [20]WU Xiang-long, FAN Wu-tu, PAN Ya-lei, ZHAI Yuan-kun, NIU Ying-bo, LI Chen-rui, MEI Qi-bing, A novel synthesis and crystal structure of AMPA receptor modulator 1-BCP[J], Chinese Journal of Synthetic Chemist, 2013, 21(1): 36-40(Chinese).

  21. [21]WU Xiang-long, PAN Ya-lei, ZHAI Yuan-kun, FAN Wu-tu, NIU Ying-bo, MEI Qi-bing, Microwave-assisted synthesis and spectral properties of novel chlorinated fluorescein derivatives[J], Chemical Reagent, 2013, 35(2): 103-106(Chinese).

     

授权专利:

[1]武祥龙,范於菟,孔祥鹤,王娟,刘莉,梅其炳,国家发明专利苯甲酰胺化合物及其制备方法ZL201110148165.X

申请专利:

[1]武祥龙,刘柳,汪晴川,卢婷利,梅其炳,利鲁唑在抑制金黄色葡萄球菌方面的应用,申请日期,20171 ,申请号:201710005771.3

[2]武祥龙,刘柳,汪晴川,卢婷利,梅其炳,2-N-乙基)-6-三氟甲氧基苯并噻唑作为抗癌药物的应用,2017.3,申请号:201710204425.8

[3]武祥龙,张飞,刘浩,陈强,董凯,卢婷利,具有荧光成像和载药双功能的介孔二氧化硅纳米材料及其制备方法,2018.11,申请号:201811250870.9

[4]武祥龙,张飞,刘浩,魏春龙,袁民政,张科强,氟比洛芬美普他酚酯药用化合物及其制备方法,2018.11,申请号:201811250880.2