尚洁

的个人主页 http://teacher.nwpu.edu.cn/1F41F0C31B1C498F91B45C7797AFBC60

基本信息 The basic information

尚洁

生命学院

博士研究生毕业

理学博士

讲师(高校)

工作经历 Work Experience

2016.12-  至今            西北工业大学 助理教授

2014.12-2016.12           康龙化成(北京)新药技术有限公司

教育经历 Education Experience

2013.03-2015.01   中国科学院化学研究所           博士

2012.10-2013.02   欧洲化学与生物学研究所         博士

2010.09-2012.09   中国科学院化学研究所           博士

2007.09-2010.06   中国科学院新疆理化技术研究所   硕士

2003.09-2007.06   安徽师范大学                   本科

教育教学 Education And Teaching

目前承担学院本科生《有机化学实验》(英)和研究生《高等有机化学实验》、《药物的设计、合成与生物活性》教学。

科学研究 Scientific Research

研究方向:

超分子自组装及功能其研究

主持项目:

  1.  主持国家自然科学基金青年项目 ,21901210,2020.01-2022.12

  2. 主持陕西省自然科学基金青年项目,2019JQ-626,2019.01-2020.12

  3.  主持中央高校基本科研业务费(新进教师科研启动费),3102017OQD045,2017.01-2018.12

学术成果 Academic Achievements

论文:

Shang, Jie; Li, Shuangran; Pan, Tiezheng; Li, Bo; Zhang, Qian; Lv, Ping; Cui, Zhiliyu; Ge, Yan; Qi, Zhenhui, Selenium-containing heterodimeric crown ether acting as an unconventional multi-responsive amphiphile in water. Chemical communications, 2020, 56(95): 15052-15055. 

Shang, Jie; Li, Bo; Shen, Xin; Pan, Tiezheng; Cui, Zhiliyu; Wang, Yangxin; Ge, Yan; Qi, Zhenhui, Selenacrown Macrocycle in Aqueous Medium: Synthesis, Redox-Responsive Self-Assembly, and Enhanced Disulfide Formation Reaction. Journal of Organic Chemistry, 2021, 86(2): 1430-1436. 

Shang, Jie; Gong, Hanlin; Zhang, Qian; Cui, Zhiliyu; Li, Shuangran; Lv, Ping; Pan, Tiezheng; Ge, Yan; Qi, Zhenhui,The dynamic covalent reaction based on diselenide-containing crown ether irradiated by visible light . Chinese Chemical Letters, 2021, 32(6): 2005-2008. 

Shang Jie, Liu, Yao, Pang, Tiezheng,  Macrocycles in Bioinspired Catalysis: From Molecules to Materials. Frontiers in Chemistry, 2021, 9, 635315

Pan, Tiezheng; Li, Jiangbo; Li, Bo; Xu, Qiangqiang; Cui, Zhiliyu; Shang, Jie; Ge, Yan; Qi, Zhenhui, Guanidinium-Responsive Crown Ether-Based Macrocyclic Amphiphile in Aqueous Medium Journal of Physical Chemistry Letters, 2021, 12(31): 7418-7422. 

Shengyi Dong, Jing Leng ,  Yexin Feng,  Ming Liu, Chloe J. Stackhouse,  Andreas Schoenhals, Leonardo Chiappisi, Lingyan Gao, Wei Chen,  Jie Shang,  Lin Jin,  Zhenhui Qi,  Christoph A. Schalley. Structural water as an essential comonomer in supramolecular polymerization , Science Advances, 2017, 11, 3(11).

Jie Shang#, Wei Zhao#, Xichen Li, Ying Wang, Hua Jiang. Aryl-triazole Foldamers Incorporating Pyridinium Motifs for Halide Anions Binding in Aqueous Media. Chem. Commun. 2016, 52,4505-4508 (共同一作)

Jie Shang, Quan Gan, Simon J. Dawson, Frédéric Rosu, Hua Jiang, Yann Ferrand, Ivan Huc. Self-Association of Aromatic Oligoamide Foldamers into Double Helices in Water. Org. Lett. 2014, 16, 4992-4995.

Jie Shang, Wen Si, Wei Zhao, Yanke Che, Jun-Li Hou, Hua Jiang. Preorganized Aryltriazole Foldamers as Effective Transmembrane Transporters for Chloride Anion. Org. Lett. 2014, 16, 4008-4011.

(4) Jie Shang, Nolan M. Gallagher, Fusheng Bie, Qiaolian Li, Yanke Che, Ying Wang, Hua Jiang. Aromatic Triazole Foldamers Induced by C–H···X (X = F, Cl) Intramolecular Hydrogen Bonding. J. Org. Chem. 2014, 79, 5134-5144.

Quan Gan, Jie Shang, Brice Kauffmann, Ying Wang, Fusheng Bie, Hua Jiang. A highly stable double helix of aromatic oligoamide comprised of fused ring aromatic units Tetrahedron, 2012, 68, 4479-4484.

Tao Pang, Jie Shang, Qin-Wan Yang, Yu Sun, An-Xin Wu, Hua Jiang. An unprecedented triple helix based on the tetrameric assembly of a macrocycle driven by weak C-H···π and C-H···O interactions. CrystengComm, 2012, 14, 5170-5173.

Fusheng Bie, Ying Wang, Jie Shang, Nolan M. Gallagher, Hua Jiang. Synergistic Recognition of Halide Anions and Saccharides by Oligohydrazide Foldamers. Eur. J. Org. Chem. 2013, 8135-8144.

专利:

生物源大环分子的纳米药物及其制备方法  葛岩; 潘铁铮; 沈鑫; 金林; 尚洁; 王杨鑫; 戚震辉, 2018-10-31, 中国, ZL201811286662.4.  

具有光动治疗活性的竹红菌素磷脂纳米盘、其制备方法及应用,葛岩; 潘铁铮; 沈鑫; 金林; 尚洁; 王杨鑫; 戚震辉, 2019-1-4, 中国, ZL201910007555.1.