张文娟


的个人主页 http://teacher.nwpu.edu.cn/2017010007

基本信息 The basic information

张文娟

生命学院

博士研究生毕业

理学博士

讲师(高校)

生物学

工作经历 Work Experience

2020年7月-至今             西北工业大学生命学院,硕士生导师

2017年7月-2020年7月     西北工业大学生命学院,博士后

2017年1月-至今               西北工业大学生命学院 助理教授



Jul 2017-Jul 2020     Postdoctor, School of Life Sciences, Northwestern Polytechnical University

Jul 2020 -now           Master’s Supervisor, School of Life Sciences, Northwestern Polytechnical University

Jan 2017-now           Assistant Professor, School of Life Sciences, Northwestern Polytechnical University

教育经历 Education Experience

2012/09-2016/12   西北农林科技大学 生物信息学 理学 博士

2009/09-2012/06   西北农林科技大学  环境工程    工学 硕士


2012/09-2016/12,PhD, Bioinformatics, Northwest A&F University

2009/09-2012/06,  Master, Environmental Engineering, Northwest A&F University



教育教学 Education And Teaching

本科生全英文课程 《Zoology》(动物学)和《Genetics》(遗传学)

本科生综合素养课程《生命科学导论》

研究生课程 《航天医学工程》


Undergraduate Courses:《Zoology》、《Genetics》

Undergraduate Courses:《Introduction of Life Sciences》

Graduate Courses:《Aerospace Medical Engineering》



招生信息 Admission Information

每年招收对生物信息学、医学大数据分析、骨代谢研究和系统生物学等方向感兴趣的硕士研究生。
欢迎数学、生物、计算机等相关专业的同学加入合作,可先邮件联系wenjuan_zhang2017@nwpu.edu.cn

科学研究 Scientific Research

1. 主持国家自然基金(青年项目),81901917,CD40L参与模拟失重促进破骨细胞分化的骨免疫机制研究,2020.01-2022.12,20万元;

2. 主持中国博士后科学基金(面上项目),2017M623249,基于网络药理学探讨黄芪心脑同治的物质基础和作用机制,2017.10-2019.10,5万元;

3. 主持中央高校基本科研业务专项资金资助(科研启动费),3102017OQD050,黄芪多靶协同心脑同治的物质基础和分子机制,2017.01-2018.12,15万元.

4. 参与国家自然科学基金(面上项目),81772017,MACF1结合CDK12参与模拟失重抑制骨形成的作用及机制,2018/01-2021/12,55万元 


Fundings

1. National Natural Science Foundation of China (Grant No. 81901917). 2020.01-2022.12, RMB 200000

2. China Postdoctoral Science Foundation (Grant No.2017M623249). 2017.10-2019.10, RMB 50000

3. The Fundamental Research Funds for the Central Universities (Grant No. 3102017OQD050). 2017.01-2018.12, RMB 150000

4. National Natural Science Foundation of China (Grant No. 81772017). 2018.01-2021.12, RMB 550000

学术成果 Academic Achievements

(1) Wenjuan Zhang, Ying Huai, Zhiping Miao, Airong Qian*, Yonghua Wang*. Systems Pharmacology for Investigation of the Mechanisms of action of Traditional Chinese Medicine in Drug Discovery. Frontiers in Pharmacology, 2019 July 11, 10:743.

(2) Wenjuan Zhang#, Kaiyue Xue#, Yongguang Gao#, Ying Huai, Wang Wei, Miao Zhiping, Dang Kai, Jiang Shanfeng, Qian Airong*. Systems pharmacology dissection of action mechanisms of Dipsaci Radix for osteoporosis. Life sciences, 2019, Aug 30, 235:116820.

(3) Wenjuan Zhang, Ying Huai, Zhiping Miao, Chu Chen, Mohamed Shahen, Siddiq Ur Rahman, Mahmoud Alagawany, Mohamed E. Abd El-Hack*, Heping Zhao*, Airong Qian*. Systems pharmacology approach to investigate the molecular mechanisms of herb Rhodiola rosea L. radix. Drug Development Industrial Pharmacology, 2018 Nov 17:1-9.

(4) Wenjuan Zhang#Ying Huai#, Wei Wang, Kaiyue Xue, Lei Chen, Chu Chen*, Airong Qian*. A Retrospective Cohort Study on the Risk Factors of Deep Vein Thrombosis (DVT) for Traumatic Fracture Patients at Honghui Hospital. BMJ Open, 2019 Mar 3; 9(3):e024247.

(5) Wenjuan Zhang, Qin Tao, Zihu Guo, Yingxue Fu, Xuetong Chen, Piar Ali Shar, Mohamed Shahen, Jinglin Zhu, Jun Xue, Yaofei Bai, Zhezhong Wang, Wei Xiao*, Yonghua Wang*. Systems Pharmacology Dissection of the Integrated Treatment for Co-Occurring Disorders by Chinese medicine: Cardiovascular and Gastrointestinal Disorders. Scientific Reports, 2016 Sep 6; 6:32400.

(6) Wenjuan Zhang, Yaofei Bai, Yonghua Wang*, Wei Xiao*. Polypharmacology in drug discovery: a review from systems pharmacology perspective. Current Pharmaceutical Design, 2016 22(21):3171-81.

(7) Haixing Yang#, Wenjuan Zhang#, Chao Huang, Wei Zhou, Yao Yao, Zhenzhong Wang, Yan Li, Wei Xiao, Yonghua Wang*. A novel systems pharmacology model for herbal medicine injection: a case using reduning injection. BMC Complement Alternative Medicine. 2014 Nov 4; 14:430.

(8)   张文娟, 王永华*. 系统药理学原理、方法及在中医药中的应用.世界中医药. 2015, 10(2): 280-286.

(9)  Jianling Liu#, Ke Sun#, Chuli Zheng, Xuetong Chen, Wenjuan Zhang, Zhenzhong Wang, Piar Ali Shar, Wei Xiao, Yonghua Wang*. Pathway as a Pharmacological Target for Herbal Medicines: An Investigation from Reduning Injection. PLOS ONE. 2015 Apr 1; 10(4): e0123109.

(10) Yuan Wang, Zihu Guo, Xuetong Chen, Wenjuan Zhang, Aiping Lu, Yonghua Wang*. Multi-scale modeling of cell survival and death mediated by p53 network: A Systems Pharmacology Framework. Molecular BioSystems. 2015 Nov 11(11):3011-21.

(11) Piar Ali Shar, Weiyang Tao, Shuo Gao, Chao Huang, Bohui Li, Wenjuan Zhang, Mohamed Shahen, Chunli Zheng, Yaofei Bai, Yonghua Wang*. Pred-binding: large-scale protein–ligand binding affinity prediction. Journal of Enzyme Inhibition and Medicinal Chemistry. 2016, Feb 18:1-8.

(12)  Weiyang Tao#, Bohui Li#, Shuo Gao, Yaofei Bai, Piar Ali Shar, Wenjuan Zhang, Zihu Guo, Ke Sun, Yingxue Fu, Chao Huang, Chunli Zheng, Jiexin Mu, Tianli Pei,Yuan Wang, Yan Li, Yonghua Wang*. CancerHSP: anticancer herbs database of systems pharmacology. Scientific Reports. 2015 Jun 15; 5:11481.

(13) Peng Li#, Chao Huang#, Yingxue Fu#, Jinan Wang#, Ziyin Wu, Jinlong Ru, Chunli Zheng, Zihu Guo, Xuetong Chen, Wei Zhou, Wenjuan Zhang, Yan Li, Jianxin Chen, Aiping Lu, Yonghua Wang*. Large-scale exploration and analysis of drug combinations. Bioinformatics. 2015 Jun 15; 31(12):2007-16.

(14) Bo Zhang#, Yingxue Fu#, Chao Huang#, Chunli Zheng#, Ziyin Wu#, Wenjuan Zhang, Xiaoyan Yang, Fukai Gong, Yuerong Li, Xiaoyu Chen, Shuo Gao, Xuetong Chen, Yan Li, Aiping Lu, Yonghua Wang*. New strategy for drug discovery by large-scale association analysis of molecular networks of different species. Scientific Reports. 2016 Feb 25; 6:21872.

(15) Mohamed Shahen#, Zihu Guo#, Akhtar Hussain Shar#, Reham Ebaid, Qin Tao, Wenjuan Zhang, Ziyin Wu, Yaofei Bai, Yingxue Fu, Chunli Zheng, He Wang, Piar Ali Shar, Jianling Liu, Zhenzhong Wang, Wei Xiao*, Yonghua Wang*. Dengue virus causes changes of MicroRNA genes regulatory network revealing potential targets for antiviral drugs. BMC Systems Biology. 2018 12