印崇


的个人主页 http://teacher.nwpu.edu.cn/2019030027

基本信息 The basic information

印崇

生命学院

博士研究生毕业

工学博士

航空宇航科学-人机与环境工程

教育经历 Education Experience

2005.09——2009.07    吉林大学            生物技术        本科

2009.09——2012.06    吉林大学            动物遗传育种    硕士

2012.08——2013.04  密西西比大学医学中心  药理学          PHD(未完成)

2014.03——2018.12   西北工业大学          生物医学工程   博士

 

Institution:       Jilin University (09/2005-06/2009)

Major:           Biotechnology

Degree:          Bachelor of Science


Institution:       Jilin University (09/2009-06/2012)

Major:           Animal Genetics, Breeding and Reproduction

Degree:          Master of science in Agriculture

Research Direction:  SNP screening of swines.

 

Institution:       University of Mississippi Medical Center (06/2012 - 05/2013)

Major:           Pharmacology

Degree:          Graduate Student (incomplete)

Research Direction:  Cancer Stem Cell, Hypertension.

 

Institution:       Northwestern Polytechnical University (03/2014-12/2018)

Major:          Biomedical engineering

Degree:         PHD

Research Direction:  Gene editing of Non-coding RNAs regulating osteoporosis.

 

教育教学 Education And Teaching

荣誉获奖 Awards Information

2016年8月,获美国骨矿物研究学术年会青年学者旅行奖金;

2018年11月,获陕西省细胞生物学学会青年优秀论文三等奖;

 

2016.8 Young investgater travel grant in ASBMR annual conference, Atlanta, USA.

2018.11 Young investgater article grant (class 3) in Shaanxi Society of Cell Biology, Xian, China.

 

科学研究 Scientific Research

1. 力学敏感MACF1对成骨细胞分化及骨形成的调控及分子机制;

2. 骨形成相关非编码RNA的筛选及功能研究;

3. 非编码RNA的成骨靶向基因编辑技术探索


1. Mechano-sensitive MACF1 regulates osteoblast differentiation and bone formation and its molecular pattern.

2. Screening and functional analysis of osteogenic noncoding RNAs.

3. Gene editing of osteogenic non-coding RNAs.






学术成果 Academic Achievements

   

1. Chong Yin, Yan Zhang, Lifang Hu, Ye Tian, Zhihao Chen, Dijie Li, FanZhao, Peihong Su, Xiaoli Ma, Ge Zhang, Zhiping Miao, Liping Wang, Airong Qian, Cory J. Xian. Mechanical unloading reduces microtubule actin crosslinking factor 1 expression to inhibit β-catenin signaling and osteoblast proliferation: Mechano-sensitive MACF1 in osteoblasts. J Cell Physiol, 2018 Jul;233(7): 5405-5419.  (Journal Inside Front Cover)

2. Chong Yin, Ye Tian, Yang Yu, Haoyu Wang, Zhixiang Wu, Zhizhan Huang, Yan Zhang, Dijie Li, Chaofei Yang, Xue Wang, Airong Qian: A novel long noncoding RNA AK016739 inhibits osteoblast differentiation and bone formation. J Cell Physiol, 2019 Jul;234(7):11524-11536.

3. Yan Zhang, Chong Yin, Lifang Hu, Zhihao Chen, Fan Zhao, Dijie Li, Jianhua Ma, Xiaoli Ma, Peihong Su, Wuxia Qiu, Chaofei Yang, Pai Wang, Siyu Li, Ge Zhang, Liping Wang, Airong Qian, Cory J. Xian. MACF1 Overexpression by Transfecting the 21-kbp Large Plasmid PEGFP-C1A-ACF7 Promotes Osteoblast Differentiation and Bone Formation. Hum Gene Ther, 2018 Feb;29(2):259-270.(co-first author)

4. Lifang Hu, Peihong Su, Chong Yin, Yan Zhang, Runzhi Li, Kun Yan, Zhihao Chen, Dijie Li, Ge Zhang, Liping Wang, Zhiping Miao, Airong Qian, Cory J Xian. Microtubule actin crosslinking factor 1 promotes osteoblast differentiation by promoting β-catenin/TCF1/Runx2 signaling axis. J Cell Physiol. 2018  Feb;233(2):1574-1584.

5. Yang Wang, ZhiHao Chen, Chong Yin, JianHua Ma, DiJie Li, Fan Zhao, YuLong Sun, LiFangHu, Peng Shang, AiRong Qian. GeneChip Expression Profiling Reveals the Alterations of Energy Metabolism Related Genes in Osteocytes under Large Gradient High Magnetic Fields. PLoS One. 2015 Jan 30;10(1).

6. Shilian Xu, Jiaru Yang, Chong Yin, Xiaohua Zhao. The dominance of bacterial genotypes leads to susceptibility variations under sublethal antibiotic pressure. Future Microbiol. 2018 Feb;13:165-185.  (Journal Inside Front Cover)

 

专利申请:

1. 印崇,邢沈阳,孙博兴,赵志辉.多重PCR和多重酶切检测猪主要肉质基因多态性的方法201110298964.5

2. 骞爱荣,印崇,苗治平,张琰,胡丽芳,陈志浩,赵帆,李迪杰,马剑华,苏佩红,马小莉,仇伍霞,杨超飞,李思宇,王牌。长链非编码RNA Lnc-DIF的应用。201710036464.1

3. 骞爱荣,胡丽芳,印崇,赵帆,陈志浩,张琰,马剑华,苏佩红,李迪杰,仇伍霞,马小莉,王牌。MACF1基因及其表达产物在制备诊断和治疗骨质疏松症药物中的应用。201610530383.2

4. 骞爱荣,胡丽芳,印崇,张琰,马剑华,赵帆,陈志浩,李迪杰,李思宇,马小莉,仇伍霞,杨超飞,王牌,苏佩红。miR-489-3p在制备诊断和治疗人骨质疏松症药物中的应用。201610504743.1