张子绘


的个人主页 http://teacher.nwpu.edu.cn/A8A55DDEC0191D44E053640A280A0D73

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基本信息 The basic information

张子绘

医学研究院

博士研究生毕业

医学博士

基础医学

zhangzh_0215@163.com

招生信息 Admission Information

教育经历 Education Experience

2013/09-2020/04:西安交通大学,病理学与病理生理学专业,硕博,导师:汪南平教授

2008/09-2013/07:大连大学,临床医学专业,学士

工作经历 Work Experience

2020/06-至今:西北工业大学,医学研究院,博士后,导师:马恒教授

科学研究 Scientific Research

主要从事心血管疾病的研究,累计发表SCI论文13篇。

学术成果 Academic Achievements

代表性论文:

1)Xin Nie#; Weiqi Tang#; Zihui Zhang; Chunmiao Yang; Lei Qian; Xinya Xie; Erjiao Qiang; Jingyang Zhao; Wenfei Zhao; Lei Xiao*; Nanping Wang*; Procyanidin B2 mitigates endothelial endoplasmic reticulum stress through a PPARδ-Dependent mechanism, Redox Biology, 2020,37:101728-101738. (IF=9.986)

2)Zhang Zihui, Xie Xinya, Yao Qinyu, Liu Jia, Tian Ying, Yang Chunmiao, Xiao Lei*, Wang Nanping*. PPARdelta agonist prevents endothelial dysfunction via induction of dihydrofolate reductase gene and activation of tetrahydrobiopterin salvage pathway. British Journal of Pharmacology, 2019, 176(16): 2945-2961. (IF=7.73)

3)Meiqian Zhang; Zihui Zhang; Xinya Xie; Qinyu Yao; Jia Liu; Baochang Lai; Lei Xiao*; Nanping Wang*; Xenobiotic pregnane X receptor promotes neointimal formation in balloon-injured rat carotid arteries, Journal of Cellular Physiology, 2019, 234(4): 4342-4351. (IF=5.546)

4)Xinya Xie; Zihui Zhang; Xinfeng Wang; Zhenyu Luo; Baochang Lai; Lei Xiao*; Nanping Wang*; Stachydrine protects eNOS uncoupling and ameliorates endothelial dysfunction induced by homocysteine, Molecular Medicine, 2018, 24(1): 1-10. (IF=4.096)

5)Qinyu Yao; Jia Liu; Zihui Zhang; Fan Li; Chao Zhang; Baochang Lai; Lei Xiao; Nanping Wang*; Peroxisome proliferator activated receptor gamma (PPARgamma) induces the gene expression of integrin alphaVbeta5 to promote macrophage M2 polarization, The Journal of Biological Chemistry, 2018, 293(43): 16572-16582. (IF=4.238)

6)Zhang Zihui#, Jiang Manli#, Xie Xinya, Yang Haixia, Wang Xinfeng, Xiao Lei*, Wang Nanping*. Oleanolic acid ameliorates high glucose-induced endothelial dysfunction via PPARdelta activation. Scientific Reports, 2017, 7:40237-40243. (IF=3.998)

7)Xiao Lei#, Zhang Zihui#, Luo Xiaoqin, Yang Haixia, Li Fan, Wang Nanping*. Retinoid acid receptor-related orphan receptor alpha (RORalpha) regulates macrophage M2 polarization via activation of AMPKalpha. Molecular Immunology, 2016, 80:17-23. (IF=3.641)

8)Jiahua Ni; Zihui Zhang; Xiaoqin Luo; Lei Xiao; Nanping Wang*; Plasticizer DBP Activates NLRP3 Inflammasome through the P2X7 Receptor in HepG2 and L02 Cells, Journal of Biochemical and Molecular Toxicology, 2016, 30(4): 178-185. (IF=3.606)

9)Xiaoqin Luo; Zhenyu Luo; Zihui Zhang; Haixia Yang; Baochang Lai; Qinyu Yao; Lei Xiao; Nanping Wang*; Homocysteine upregulates hepcidin expression through BMP6/SMAD signaling pathway in hepatocytes, Biochemical and Biophysical Research Communications, 2016, 471(2): 303-308. (IF=2.985)