基本信息 The basic information
招生信息 Admission Information
教育经历 Education Experience
2013/09-2020/04：西安交通大学，病理学与病理生理学专业，硕博，导师：汪南平教授
2008/09-2013/07：大连大学，临床医学专业，学士
工作经历 Work Experience
2020/06-至今：西北工业大学，医学研究院，博士后，导师：马恒教授
科学研究 Scientific Research
主要从事心血管疾病的研究，累计发表SCI论文13篇。
学术成果 Academic Achievements
代表性论文：
1）Xin Nie#; Weiqi Tang#; Zihui Zhang; Chunmiao Yang; Lei Qian; Xinya Xie; Erjiao Qiang; Jingyang Zhao; Wenfei Zhao; Lei Xiao*; Nanping Wang*; Procyanidin B2 mitigates endothelial endoplasmic reticulum stress through a PPARδ-Dependent mechanism, Redox Biology, 2020,37:101728-101738. (IF=9.986)
2）Zhang Zihui, Xie Xinya, Yao Qinyu, Liu Jia, Tian Ying, Yang Chunmiao, Xiao Lei*, Wang Nanping*. PPARdelta agonist prevents endothelial dysfunction via induction of dihydrofolate reductase gene and activation of tetrahydrobiopterin salvage pathway. British Journal of Pharmacology, 2019, 176(16): 2945-2961. (IF=7.73)
3）Meiqian Zhang; Zihui Zhang; Xinya Xie; Qinyu Yao; Jia Liu; Baochang Lai; Lei Xiao*; Nanping Wang*; Xenobiotic pregnane X receptor promotes neointimal formation in balloon-injured rat carotid arteries, Journal of Cellular Physiology, 2019, 234(4): 4342-4351. (IF=5.546)
4）Xinya Xie; Zihui Zhang; Xinfeng Wang; Zhenyu Luo; Baochang Lai; Lei Xiao*; Nanping Wang*; Stachydrine protects eNOS uncoupling and ameliorates endothelial dysfunction induced by homocysteine, Molecular Medicine, 2018, 24(1): 1-10. (IF=4.096)
5）Qinyu Yao; Jia Liu; Zihui Zhang; Fan Li; Chao Zhang; Baochang Lai; Lei Xiao; Nanping Wang*; Peroxisome proliferator activated receptor gamma (PPARgamma) induces the gene expression of integrin alphaVbeta5 to promote macrophage M2 polarization, The Journal of Biological Chemistry, 2018, 293(43): 16572-16582. (IF=4.238)
6）Zhang Zihui#, Jiang Manli#, Xie Xinya, Yang Haixia, Wang Xinfeng, Xiao Lei*, Wang Nanping*. Oleanolic acid ameliorates high glucose-induced endothelial dysfunction via PPARdelta activation. Scientific Reports, 2017, 7:40237-40243. (IF=3.998)
7）Xiao Lei#, Zhang Zihui#, Luo Xiaoqin, Yang Haixia, Li Fan, Wang Nanping*. Retinoid acid receptor-related orphan receptor alpha (RORalpha) regulates macrophage M2 polarization via activation of AMPKalpha. Molecular Immunology, 2016, 80:17-23. (IF=3.641)
8）Jiahua Ni; Zihui Zhang; Xiaoqin Luo; Lei Xiao; Nanping Wang*; Plasticizer DBP Activates NLRP3 Inflammasome through the P2X7 Receptor in HepG2 and L02 Cells, Journal of Biochemical and Molecular Toxicology, 2016, 30(4): 178-185. (IF=3.606)
9）Xiaoqin Luo; Zhenyu Luo; Zihui Zhang; Haixia Yang; Baochang Lai; Qinyu Yao; Lei Xiao; Nanping Wang*; Homocysteine upregulates hepcidin expression through BMP6/SMAD signaling pathway in hepatocytes, Biochemical and Biophysical Research Communications, 2016, 471(2): 303-308. (IF=2.985)