武祥龙

的个人主页 http://teacher.nwpu.edu.cn/wuxianglong

  被浏览次数:5973

基本信息 The basic information

武祥龙

生命学院

博士研究生毕业

博士

副教授

生物医学工程

wuxianglong@nwpu.edu.cn

工作经历 Work Experience

2013年1月至2014年4月西北工业大学生命学院讲师;2014年4月至今生命学院副教授。其中,2019年3月至2020年3月在南洋理工大学材料与科学工程学院访学。



2014.05-present Associate professor, School of Life Science, Northwestern Polytechnical University

2012.12-2014.04 Lecturer, School of Life Science, Northwestern Polytechnical University

2010.06-2012.12 Postdoctoral Fellow, School of Life Science, Northwestern Polytechnical University

 

教育经历 Education Experience

2001年至2005年西北大学材料化学专业读本科

2005年至2010年西北大学有机化学硕博连读

20107月至201212月西北工业大学生命学院博士后


2005.09-2010.06 Master Degree and Ph.D. of Organic Chemistry, College of Chemistry & Materials Science, Northwest University (China)

2001.09-2005.07 Bachelor Degree of Materials Chemistry, Department of Chemistry, Northwest University (China)


教育教学 Education And Teaching

研究方向:

荧光探针设计合成及应用、航天员空间骨丢失机理及其防护药物研究、药物设计合成及生物活性研究、生物材料;


Research interests:

fluorescent probesriluzole derivatives antitumor activity and molecular mechanismriluzole derivatives peripheral analgesic effect on neuropathic pain and their mechanism;Biologicalmaterials



主讲课程:

本科生专业课《人体解剖生理学》 

本科生专业基础课《有机化学》

本科生综合素养课《文献检索与论文写作》

研究生专业课《药物代谢与药物分析》 


Course:

Human Anatomy and PhysiologyOrganic Chemistry

Information Retrieval and Academic Writing

Pharmacokinetics and Pharmaceutical Analysis



教学荣誉

2016年首届卓越联盟青年教师讲课比赛三等奖;

2017年西北工业大学最满意教师称号;

2017年优秀班主任称号;

2018年陕西省第三届微课教学比赛三等奖

教改项目:

2016年获批1项校级在线开放课程建设项目《人体解剖生理学》;

2016年获批1项教学与考核模式改革项目;

中国大学mooc主讲《人体解剖生理学

网址链接https://www.icourse163.org/course/NWPU-1002527016

2019年《人体解剖解剖生理学》获得陕西省精品在线课程称号;

中国大学mooc主讲《文献检索与论文写作》

课程网址链接:https://www.icourse163.org/course/NWPU-1206520804



2018.5   Third Prize of Teaching Competition in Shaanxi Province

2016.06     Third Prize of Teaching Competition in Northwestern Polytechnical University

2009        Academic Scholarship for Excellent meeting paper

2002-2005   Northwest University Excellent Academic Scholarship

2002-2005   Cyrus Tang Foundation Scholarship



2016&2019 Two Massive Open Online Courses

2016&2017 Project on educational reform 


 

 

招生信息 Admission Information

硕士研究生招生专业:生物医学工程、生物与医药工程


The main major for recruiting master students: Biomedical engineering; Biological and medical engineering

科学研究 Scientific Research


国家自然科学基金青年项目(21202130),用于标记糖的荧光探针的设计合成及其示踪寡糖吸收机制研究2013~2015 

陕西省自然科学基金面上项目(2015JM2067),利鲁唑衍生物的合成及其镇痛作用机制研究2015.1-2016.12

中央高校基本科研业务费专项资金资助(3102014JKY15005),利鲁唑衍生物的合成及其镇痛作用机制研究 2014.05-2016.05

企业横向课题:(2018ME180014C180014)氟比洛芬甲酯的合成及其药物剂型研究,2018.52020.5

陕西省自然科学基金面上项目 (No.2019JM-152) 利鲁唑及其衍生物对HeLa细胞抗肿瘤作用和机制研究,2019.12020.12

2019.3.102020.3.14  西北工业大学青年教师国际名校访学支持计划

 

2013.01-2015.12 Synthesis and design of fluorescent carbohydrate-labeling probes and study on its mechanism of absorption, the National Natural Science Foundation of China (No. 21202130)

2014.04-2016.04 Research on riluzole derivatives analgesic effect on neuropathic pain and their mechanism, the Fundamental Research Funds for the Central Universities (No. 3102014JCQ15005)

2015.01-2016.12 Research on riluzole derivatives peripheral analgesic effect on neuropathic pain and their mechanism, the Natural Science Foundation Research Project of Shaanxi Province (No.2015JM2067)

2017.1-2020.12 Research on riluzole derivatives antitumor activity and molecular mechanism, the Natural Science Foundation Research Project of Shaanxi Province (No.2019JM-152)

2019.3 to 2020.3  Top International University Visiting Program for Outsanding Young scholars of Northwestern Polytechnical University




 


 

学术成果 Academic Achievements

部分学术成果:

  1. Xianglong Wu, Zhihui Chen, Wangqiao Chen, Fei Yu, Guofu Zhou*, Qinghua Xu*, and Qichun Zhang*, Two-photon absorption of butterfly-shaped carbonyl-bridged twistarene [J]. Asian Journal of Organic Chemistry 2020, 9, 579–583.

  2. Wu X L, Wang Q C, Zhang F, Liu H, Lu T L, Zhang Q C. Preparation and in vivo atinociceptive behavior of four new 2-amino-6-trifuromethoxybenzothiazole carboxylic acid derivatives [J]. ChemistrySelect 2019, 4, 9993-9998.

  3. Dong K, Lei Q, Guo R, Wu X L, Zhang Y, Cui N, Shi J Y, Lu T. Regulating intracellular ROS signal by a dual pH/reducing-responsive nanogels system promotes tumor cell apoptosis[J]. International Journal of Nanomedicine, 2019, 14, 5713-5728.

  4. Lu C B , Wu X L(co-first author), Ma H Z, Wang Q C, Wang Y K, Luo Y, Li C, XU H. Optogenetic Stimulation Enhanced Neuronal Plasticities in Motor Recovery after Ischemic Stroke[J]. Neural Plasticity, 2019, 1-9.

  5. 张飞,刘振国, 王海芳, 武祥龙*, 刘柳, 蔺旭彬, 吕文君,刘浩.2-(N-丙基)-6-三氟甲氧基苯并噻唑抗肿瘤活性研究[J]. 中国药理学通报, 2019, 35(05):644-648.

  6. Wu X L, Liu L, Li Y J, et al. Synthesis, crystal structure, and antinociceptive effects of some new riluzole derivatives[J]. Medicinal Chemistry Research, 2018, 27: 1374–1383.

  7. Jing X L, Wu X L(co-first author), et al. Reaction-Based Fluorescent Probes for rapid detection of hydrogen sulfide in vivo[J]. Analytical Methods, 2018,10:4079-4084

  8. Jing X L, Wu X L(co-first author), et al. A reversible fluorescent probe for Zn2+ and ATP in living cells andin vivo[J]. Sensors and Actuators B, 2018, 261(5):127-134.

  9. Jin X, Wu Xianglong(co-first author), Liu L, et al. Dual-Functional Fluorescein-Based Chemosensor for Chromogenic Detection of Fe3+, and Fluorgenic Detection of HOCl [J]. Journal of Fluorescence, 2017(4):2111-2117.

  10. 张飞, 刘柳, 汪晴川, 蔺旭彬, 吕文君, 梅其炳, 武祥龙*.宫颈癌HeLa细胞调控信号通路研究新进展, 化学与生物工程2018, 35(2):1-7.

  11. 汪晴川,刘柳,徐小康,盖冬玮,梅其炳,武祥龙*AMPA受体变构调节剂CX516药理学研究进展[J]. 化学与生物工程2017, 34(6):1-5.

  12. 刘柳汪晴川盖冬玮徐小康,徐强强,贺聪,陈威,梅其炳,武祥龙*利鲁唑在神经保护、镇痛及抗抑郁领域的研究进展[J]. 化学与生物工程2017, 34(2):6-9.

  13. 武祥龙*,刘柳,李游嘉,罗杰,盖冬玮,马景川,梅其炳, 2-(N-环己胺)-6-三氟甲氧基苯并噻唑的合成及其晶体结构,合成化学,20164346 ~ 349

  14. 刘柳,马景川,盖冬玮,张妍,冯昕,马梦瑶,张明,武祥龙*,用于检测巯基化合物的荧光探针的研究进展,化学与生物工程,2016021~ 7

  15. 武祥龙, 李海亮, 卢娜, 牛银波, 李晨睿, 梅其炳. 苯并噻唑衍生物的生物活性及其构效关系研究进展. 化学与生物工程, 2014, 5:1-6+9.

  16. 武祥龙. 寡糖生物活性及其标记技术研究进展. 山东化工, 2015, 44(3): 40-45.

  17. 武祥龙. 利鲁唑药理学作用研究进展. 中国药学杂志,2015, 50(14):1165-1168.

  18. 商澎, 呼延霆, 杨周岐, 武祥龙, 赵玉芬, 赵国屏, 顾逸东. 中国空间生命科学的关键科学问题和发展方向. 中国科学: 技术科学,2015, 45:1-13.

  19. X. L. Wu, W.T. Fan, Y. L. Pan, et al. Synthesis, crystal structure and anti-fatigue effects of some benzamide derivatives. Molecules 2014, 19: 1034-1046.

  20.  X. L. Wu, W.T. Fan, Y. L. Pan, et al. Synthesis, spectroscopic properties, and biological applications of eight novel chlorinated fluorescent proteins-labeling probes, J.Fluoresc. 2014, 24(3): 775-786.

  21.  X. L. Wu, X. L. Jin, Y. X. Wang, J. L. Li, Z. Shi, “Synthesis and spectral properties of novel chlorinated pH fluorescent probes”. J. Lumin. 2011, 131(4): 776-780

  22. W.T. Fan, X. L. Wu, Y. L. Pan, et al. “1-(1, 3-Benzodioxol-5-yl-carbo-nyl) piperidine, a modulator of α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor, ameliorates exercise-induced fatigue in mice”. Biol. Pharm. Bull. 2014, 37(1):13–17.

授权专利:

[1]武祥龙,范於菟,孔祥鹤,王娟,刘莉,梅其炳,国家发明专利苯甲酰胺化合物及其制备方法ZL201110148165.X

[2]武祥龙,刘柳,汪晴川,卢婷利,梅其炳,2-N-乙基)-6-三氟甲氧基苯并噻唑作为抗癌药物的应用,2017.3,专利号:ZL201710204425.8


申请专利:

[1]武祥龙,刘柳,汪晴川,卢婷利,梅其炳,利鲁唑在抑制金黄色葡萄球菌方面的应用,申请日期,20171 ,申请号:201710005771.3

[2] 武祥龙,张飞,刘浩,魏春龙,袁民政,张科强. 氟比洛芬美普他酚酯药用化合物及其制备方法, 2018.11, 申请号:201811250880.2

[3] 武祥龙,张飞,刘浩,陈强,董凯,卢婷利.具有荧光成像和载药双功能的介孔二氧化硅纳米材料的制备方法, 2018.11, 申请号:201811250870.9